Methyl 5-(tert-butoxycarbonylamino)-1-methylcyclohex-3-enecarboxylate → HCID 67285117、化合物

HRID 74998ノート

反応式

HRID 74998 の反応式
[C:1]([O:5][C:6]([NH:8][CH:9]1[CH2:14][C:13]([CH3:19])([C:15]([O:17][CH3:18])=[O:16])[CH2:12][CH:11]=[CH:10]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]>CO.[Pd]>[C:1]([O:5][C:6]([NH:8][CH:9]1[CH2:14][C:13]([CH3:19])([C:15]([O:17][CH3:18])=[O:16])[CH2:12][CH2:11][CH2:10]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

参加物

4

反応物 1

HCID 67285544Methyl 5-(tert-butoxycarbonylamino)-1-methylcyclohex-3-enecarboxylate

生成物 1

HCID 67285117HCID 67285117、化合物

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

Methyl 5-(tert-butoxycarbonylamino)-1-methylcyclohex-3-enecarboxylate, 52f, (5.59 g, 20.75 mmol) was dissolved in 100 mL of MeOH. To the stirred solution was added 5% palladium on carbon (1.11 g, 10.38 mmol) and the reaction was stirred under a hydrogen balloon for 2 days. The reaction was filtered through celite, and the filtrate was concentrated in vacuo and used without further purification.

後処理

  1. filtrationThe reaction was filtered through celite
  2. concentrationthe filtrate was concentrated in vacuo
  3. customused without further purification

出典と根拠

ORDレコード
ord-a7a8e5b9180c4b33bb94616ad6c821cd
出典データセット
uspto-grants-2014_09
特許番号
US08829007B2

反応ノート

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