4-Hydroxybenzoic Acid → Benzoic acid, 4-((1-oxodecyl)oxy)-

HRID 752

反応式

HRID 752 の反応式
[OH:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1.[C:11](Cl)(=[O:21])[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20].N1C=CC=CC=1>O>[C:11]([O:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1)(=[O:21])[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20]

参加物

5

反応物 3

HCID 1354-Hydroxybenzoic AcidHCID 1049PyridineHCID 66982Decanoyl chloride

生成物 1

HCID 3608562Benzoic acid, 4-((1-oxodecyl)oxy)-

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

10 Grams of p-hydroxybenzoic acid and 15 g of decanoic acid chloride were stirred at room temperature, and 7.2 g of pyridine was dropwise added. After the mixture was stirred for 1 day, a reaction product was poured into water, and an organic layer was extracted with dichloromethane. The organic layer was washed with 1N hydrochloric acid and dried over anhydrous sodium sulfate, the solvent was distilled off, and then residue was washed with n-hexane and then dried to give a crude end product.

後処理

  1. extractionan organic layer was extracted with dichloromethane
  2. washThe organic layer was washed with 1N hydrochloric acid
  3. dry with materialdried over anhydrous sodium sulfate
  4. distillationthe solvent was distilled off
  5. washresidue was washed with n-hexane
  6. customdried
  7. customto give a crude end product

出典と根拠

ORDレコード
ord-c218088b16c541088a933a7606f68c4c
出典データセット
uspto-grants-1998_03
特許番号
US05723069

関連ノート

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