Benzo-1,3-dioxole-5-methylamine → HCID 178460119、化合物
反応式
NCc1ccc2c(c1)OCO2.CC(C(=O)O)c1ccc(CBr)cc1.C1CCN(C1)[P+](N2CCCC2)(N3CCCC3)Br.F[P-](F)(F)(F)(F)F.CCN(C(C)C)C(C)C.CN(C)C=O>>CC(C(=O)NCc1ccc2c(c1)OCO2)c1ccc(CBr)cc1参加物
6
反応条件
- 温度
- 25 °C
後処理
- addition150 uL of MeCN/H2O (1:1) mixed solvent was dispensed separately into each plate using the 96-tip head of the Tecan Evo-200.
- addition150 uL of internal standard solution was dispensed separately into each plate using the 96-tip head of the Tecan Evo-200.
- aliquot10 uL aliquot taken from reaction vials, and added to pre-filled wells in the transfer plate.
- addition380 uL MeCN solvent were added to the transfer plate
- aliquot20 uL taken from transfer plate to filter plate 1 for LCMS analysis
- addition180 uL MeCN added to filter plate 1 for LCMS analysis
- aliquot10 uL taken from transfer plate to filter plate 2 for TOF-DESI analysis
- addition190 uL MeCN added to filter plate 2 for TOF-DESI analysis
- customthe 96-well filter plates were centrifuged for 2.5 min at 3000 RPM
出典と根拠
- ORDレコード
- ord-0e4cd057fa6f423ea2c971792b4009a2
- 出典データセット
- AIChemEco amide coupling conditions 47k dataset
反応ノート
読み込み中…