Alpha-Aminobutyric Acid → 2-(Acetylamino)butanoic acid

HRID 7535

反応式

HRID 7535 の反応式
[NH2:1][CH:2]([CH2:6][CH3:7])[C:3]([OH:5])=[O:4].[C:8](OC(=O)C)(=[O:10])[CH3:9]>C(O)(=O)C>[C:8]([NH:1][CH:2]([CH2:6][CH3:7])[C:3]([OH:5])=[O:4])(=[O:10])[CH3:9]

参加物

4

反応物 2

HCID 6657Alpha-Aminobutyric AcidHCID 7918Acetic Anhydride

生成物 1

HCID 3061072-(Acetylamino)butanoic acid

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

反応条件

温度
100 °C

実験手順

163 g (1.58 mol) 2-aminobutanoic acid are dissolved in acetic acid, and 242 g (2.37 mol) acetic anhydride are added dropwise. The mixture is stirred for 2 h at 100° C. until completion of reaction, then the solution evaporated to dryness in vacuo. The solid residue is suspended in ethyl acetate, filtered and washed with diethyl ether.

後処理

  1. customthe solution evaporated to dryness in vacuo
  2. filtrationfiltered
  3. washwashed with diethyl ether

出典と根拠

ORDレコード
ord-4825907718a34102b76de664069c39ba
出典データセット
uspto-grants-2006_08
特許番号
US07087605B2

関連ノート

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