Hydrazine hydrate (1:1) → HCID 178422720、化合物

HRID 75511

反応式

HRID 75511 の反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7](=O)[CH2:8][C:9](=O)[CH3:10])[CH:2]=1.O.[NH2:14][NH2:15]>CO>[CH3:10][C:9]1[CH:8]=[C:7]([C:3]2[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=2)[NH:14][N:15]=1

参加物

4

反応物 2

HCID 24654Hydrazine hydrate (1:1)HCID 3001601-(Pyridin-3-yl)butane-1,3-dione

生成物 1

HCID 178422720HCID 178422720、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

1-Pyridin-3-yl-butane-1,3-dione (step 1) (500 mg, 3.06 mmol) was dissolved in MeOH (20 ml). Hydrazine monohydrate (230 mg, 223 μl, 4.60 mmol) was added and the resulting mixture was stirred at RT for 1 hour. After cooling to RT, the solvent was removed in vacuo. The crude residue was dissolved in DCM, dried over (MgSO4) filtered and concentrated in vacuo to afford the title compound which was used without further purification.

後処理

  1. temperatureAfter cooling to RT
  2. customthe solvent was removed in vacuo
  3. dissolutionThe crude residue was dissolved in DCM
  4. dry with materialdried over (MgSO4)
  5. filtrationfiltered
  6. concentrationconcentrated in vacuo

出典と根拠

ORDレコード
ord-8ec2aed3230440bc91c59ac10514a757
出典データセット
uspto-grants-2014_09
特許番号
US08835444B2

関連ノート

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