tert-butyl 5-benzoylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate → HCID 58312740、化合物

HRID 75683

反応式

HRID 75683 の反応式
[C:1]([N:9]1[CH2:13][CH:12]2[CH2:14][N:15](C(OC(C)(C)C)=O)[CH2:16][CH:11]2[CH2:10]1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(O)(C(F)(F)F)=O.C(Cl)Cl>[CH2:10]1[CH:11]2[CH2:16][NH:15][CH2:14][CH:12]2[CH2:13][N:9]1[C:1]([C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)=[O:8]

参加物

4

反応物 1

HCID 71285668tert-butyl 5-benzoylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate

生成物 1

HCID 58312740HCID 58312740、化合物

試薬・触媒・溶媒 2

HCID 6344Dichloromethane溶媒HCID 6422Trifluoroacetic acid溶媒

実験手順

tert-butyl 5-benzoylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate (100 mg) was dissolved in 10% TFA solution in CH2Cl2 (10 mL). The reaction was stirred at room temperature for 24 hours. After removal of solvents, the residue, (hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)(phenyl)methanone, was used in the further reactions without purification.

後処理

  1. customAfter removal of solvents
  2. customthe residue, (hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)(phenyl)methanone, was used in the further reactions without purification

出典と根拠

ORDレコード
ord-fe45223192ee436fafefecb4c2ceabd6
出典データセット
uspto-grants-2014_09
特許番号
US08835454B2

関連ノート

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