Nitric Acid → 4-(Benzyloxy)-5-methoxy-2-nitrobenzaldehyde
反応式
[CH2:1]([O:8][C:9]1[CH:16]=[CH:15][C:12]([CH:13]=[O:14])=[CH:11][C:10]=1[O:17][CH3:18])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N+:19]([O-])([OH:21])=[O:20]>>[CH2:1]([O:8][C:9]1[C:10]([O:17][CH3:18])=[CH:11][C:12]([CH:13]=[O:14])=[C:15]([N+:19]([O-:21])=[O:20])[CH:16]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1参加物
3
実験手順
Nitric acid (100 mL) was cooled to 0° C., 4-benzyloxy-3-methoxybenzaldehyde (20 g, 82.55 mmol) was added dropwise, and the mixture was stirred at room temperature for 2 hours. After completion of the reaction, distilled water was added thereto and the mixture was stirred for 30 min, followed by filtration of the solid to obtain the title compound (20.52 g, 87%).
後処理
- customAfter completion of the reaction
- distillationdistilled water
- additionwas added
- stirringthe mixture was stirred for 30 min
- filtrationfollowed by filtration of the solid
出典と根拠
- ORDレコード
- ord-829124fe01be4f0d845d1c70aca583ab
- 出典データセット
- uspto-grants-2014_09
- 特許番号
- US08835458B2
反応ノート
読み込み中…