Ethanol → 2-Oxopyrrolidine-3-carboxylic acid
反応式
C(OC([N:6]1[CH2:10][CH2:9][CH2:8][C:7]1=[O:11])=O)C.[OH-:12].[Na+].C[CH2:15][OH:16]>>[O:11]=[C:7]1[CH:8]([C:15]([OH:16])=[O:12])[CH2:9][CH2:10][NH:6]1参加物
4
実験手順
To 0.50 g (3.18 mmol) 2-oxo-pyrollidine-carboxylic acid ethyl ester in 10 mL EtOH are added 5 mL aq. NaOH (1M) solution. The reaction mixture is stirred at r.t. for 3 h. The EtOH is removed in vacuo and the residue is diluted with water and acidified with aq. HCl (2M) solution. The resulting precipitate is filtered and dried.
後処理
- customThe EtOH is removed in vacuo
- additionthe residue is diluted with water
- filtrationThe resulting precipitate is filtered
- customdried
出典と根拠
- ORDレコード
- ord-eb7275050f334e848da4cf494465570b
- 出典データセット
- uspto-grants-2014_09
- 特許番号
- US08835472B2
反応ノート
読み込み中…