Thionyl Chloride → 2-Formyl-5-(trifluoromethyl)benzoyl chloride

HRID 78548ノート

反応式

HRID 78548 の反応式
[CH:1]([C:3]1[CH:11]=[CH:10][C:9]([C:12]([F:15])([F:14])[F:13])=[CH:8][C:4]=1[C:5](O)=[O:6])=[O:2].S(Cl)([Cl:18])=O>>[CH:1]([C:3]1[CH:11]=[CH:10][C:9]([C:12]([F:15])([F:14])[F:13])=[CH:8][C:4]=1[C:5]([Cl:18])=[O:6])=[O:2]

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 866408592-Formyl-5-(trifluoromethyl)benzoic acid

生成物 1

HCID 871140332-Formyl-5-(trifluoromethyl)benzoyl chloride

実験手順

A solution of Example 375A (0.6 g) and thionyl chloride (3.27 g, 27.5 mmol) was refluxed for 2 hr. The reaction solution was cooled to room temperature, concentrated, azeotroped with toluene, and used without further purification.

後処理

  1. concentrationconcentrated
  2. customazeotroped with toluene
  3. customused without further purification

出典と根拠

ORDレコード
ord-3ccb49dfcfe84c628b4d5ddde61629b1
出典データセット
uspto-grants-2014_09
特許番号
US08841334B2

反応ノート

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