Ethanol → 6-Methoxy-1-propyl-indan
反応式
CO[C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][CH:11]=1)[CH:8]([CH2:12][CH2:13][CH3:14])[CH:7]=[CH:6]2.[CH2:15]([OH:17])C>[Pd]>[CH3:15][O:17][C:11]1[CH:10]=[C:9]2[C:5]([CH2:6][CH2:7][CH:8]2[CH2:12][CH2:13][CH3:14])=[CH:4][CH:3]=1参加物
4
実験手順
The mixture of indenes from step 1 (1.24 g, approx. 6.1 mmol) was dissolved in ethanol (40 mL), treated with 10% Pd on carbon (58 mg), and hydrogenated at 40 psi and room temperature for 60 minutes. The catalyst was removed by filtration and the filtrate was evaporated under vacuum to provide a mixture (1.287 g) of 6-methoxy-1-propyl-indan and 5-methoxy-1-propyl-indan in nearly a 1:1 ratio.
後処理
- customThe catalyst was removed by filtration
- customthe filtrate was evaporated under vacuum
出典と根拠
- ORDレコード
- ord-f7b0953821a446b293b603d05a892eeb
- 出典データセット
- uspto-grants-2006_08
- 特許番号
- US07087599B2
反応ノート
読み込み中…