Phenyltrimethylammonium bromide dibromide → HCID 58545558、化合物
反応式
[S:1]1[C:5]([C:6](=[O:8])[CH3:7])=[CH:4][CH:3]2[S:9][CH:10]=[CH:11][CH:2]12.[Br-:12].[Br-].[Br-].C1([N+](C)(C)C)C=CC=CC=1.C1([N+](C)(C)C)C=CC=CC=1.C1([N+](C)(C)C)C=CC=CC=1>C1COCC1>[Br:12][CH2:7][C:6]([C:5]1[S:1][CH:2]2[CH:11]=[CH:10][S:9][CH:3]2[CH:4]=1)=[O:8]参加物
4
実験手順
1-(3a,6a-Dihydro-thieno[3,2-b]thiophen-2-yl)-ethanone (453 mg, 2.48 mmol) was dissolved in THF (12 mL) and phenyltrimethylammonium tribromide (932 mg, 2.48 mmol) was added. After stirring for 1 h, the suspension was filtered over CELITE. The filtrate was diluted with diethyl ether, then washed with saturated aqueous NaHCO3 and brine then dried over MgSO4, filtered and concentrated to afford the title compound which was carried on without purification.
後処理
- filtrationthe suspension was filtered over CELITE
- additionThe filtrate was diluted with diethyl ether
- washwashed with saturated aqueous NaHCO3 and brine
- dry with materialthen dried over MgSO4
- filtrationfiltered
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-7e09ee270ba2465f88cc80618bdc441c
- 出典データセット
- uspto-grants-2014_09
- 特許番号
- US08841278B2
反応ノート
読み込み中…