Tetrahydrofuran → 2-Hydroxy-4-(5-fluoro-2-methoxyphenyl)-4-methyl-2-trifluoromethyl-pentanol

反応式

[Al+3:2].[F:7][c:8]1[cH:9][cH:10][c:11]([O:27][CH3:28])[c:12]([C:14]([CH2:15][C:16]([C:17](=[O:18])[OH:19])([C:20]([F:21])([F:22])[F:23])[OH:24])([CH3:25])[CH3:26])[cH:13]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3].[O:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1>>[F:7][c:8]1[cH:9][cH:10][c:11]([O:27][CH3:28])[c:12]([C:14]([CH2:15][C:16]([CH2:17][OH:18])([C:20]([F:21])([F:22])[F:23])[OH:24])([CH3:25])[CH3:26])[cH:13]1