Diethyl (trichloromethyl)phosphonate → 1-[4-Chloro-3-(2-chloro-2-diethoxyphosphorylethenyl)phenyl]-3,4-dimethylpyrrole-2,5-dione

反応式

[Cl:18][c:19]1[c:20]([CH:21]=[O:22])[cH:23][c:24]([N:27]2[C:28](=[O:35])[C:29]([CH3:34])=[C:30]([CH3:33])[C:31]2=[O:32])[cH:25][cH:26]1.[Cl:1][C:2]([P:3]([O:4][CH2:5][CH3:6])(=[O:7])[O:8][CH2:9][CH3:10])([Cl:11])[Cl:12].[Li:13][CH2:14][CH2:15][CH2:16][CH3:17]>>[C:2]([P:3]([O:4][CH2:5][CH3:6])(=[O:7])[O:8][CH2:9][CH3:10])([Cl:12])=[CH:21][c:20]1[c:19]([Cl:18])[cH:26][cH:25][c:24]([N:27]2[C:28](=[O:35])[C:29]([CH3:34])=[C:30]([CH3:33])[C:31]2=[O:32])[cH:23]1

参加物

反応物 3

HCID 70085Diethyl (trichloromethyl)phosphonate

HCID 150231892-Chloro-5-(3,4-dimethyl-2,5-dioxopyrrol-1-yl)benzaldehyde

HCID 178418339Butyllithium

生成物 1

HCID 571397091-[4-Chloro-3-(2-chloro-2-diethoxyphosphorylethenyl)phenyl]-3,4-dimethylpyrrole-2,5-dione

出典と根拠

ORDレコード: ord-3a5f7d6dbb6c40f18dce9476907db28f
出典データセット: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…