Hydrochloric Acid → 6-Amino-2-methyl-3-nitrobenzoic acid
反応式
[CH3:1][C:2]1[C:10]([N+:11]([O-:13])=[O:12])=[CH:9][CH:8]=[C:7]([NH:14]C(=O)C)[C:3]=1[C:4]([OH:6])=[O:5].Cl>[OH-].[Na+]>[CH3:1][C:2]1[C:10]([N+:11]([O-:13])=[O:12])=[CH:9][CH:8]=[C:7]([NH2:14])[C:3]=1[C:4]([OH:6])=[O:5]参加物
4
反応条件
- 温度
- 95 °C
実験手順
450 ml of 2N NaOH are initially taken and 75.6 g (0.317 mol) of 2-methyl-3-nitro-6-acetamidobenzoic acid are added. The reaction mixture is then warmed to 95° C. and is stirred at this temperature for one hour. After cooling to 10° C., it is acidified by addition of 425 ml of 2N HCl, and the precipitate which deposits is filtered off with suction, washed with water and dried under reduced pressure at 50° C.
後処理
- temperatureAfter cooling to 10° C.
- filtrationthe precipitate which deposits is filtered off with suction
- washwashed with water
- customdried under reduced pressure at 50° C.
出典と根拠
- ORDレコード
- ord-36a2a540166a44e2ae3ef4e91516ef3a
- 出典データセット
- uspto-grants-1998_03
- 特許番号
- US05723415
反応ノート
読み込み中…