Tetrahydrofuran → 3-{1-Hydroxy-1-(4-fluorophenyl)-methyl}-N-methyl-benzamide

反応式

[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH:7][CH3:8])[cH:9][cH:10][cH:11]1.[CH2:12]([Li:13])[CH2:14][CH2:15][CH3:16].[CH3:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36].[F:17][c:18]1[cH:19][cH:20][c:21]([CH:22]=[O:23])[cH:24][cH:25]1.[O:26]1[CH2:27][CH2:28][CH2:29][CH2:30]1>>[c:2]1([CH:22]([c:21]2[cH:20][cH:19][c:18]([F:17])[cH:25][cH:24]2)[OH:23])[cH:3][c:4]([C:5](=[O:6])[NH:7][CH3:8])[cH:9][cH:10][cH:11]1