Ethyl bromoacetate → Ethyl (1H-pyrazolo[3,4-b]pyridin-1-yl)acetate

反応式

[NH:1]1[C:5]2=[N:6][CH:7]=[CH:8][CH:9]=[C:4]2[CH:3]=[N:2]1.Br[CH2:11][C:12]([O:14][CH2:15][CH3:16])=[O:13]>>[N:1]1([CH2:11][C:12]([O:14][CH2:15][CH3:16])=[O:13])[C:5]2=[N:6][CH:7]=[CH:8][CH:9]=[C:4]2[CH:3]=[N:2]1

参加物

反応物 2

HCID 7748Ethyl bromoacetate

HCID 27558501H-pyrazolo(3,4-b)pyridine

生成物 1

HCID 57642798Ethyl (1H-pyrazolo[3,4-b]pyridin-1-yl)acetate

実験手順

The title compound was prepared according to the method described for Preparation 93 using 1H-pyrazolo[3,4-b]pyridine and ethyl bromoacetate to afford the title compound as an off-white solid in 49% yield, 210 mg.

後処理

customThe title compound was prepared

出典と根拠

ORDレコード: ord-bb2d9ff9f1d140ac88c6645463ceb036
出典データセット: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08846698B2

反応ノート

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