Dimethylformamide → 4-[2-fluoro-4-(3-hydroxy-1-propynyl)anilino]-N-(3-hydroxypropyl)-1-methyl-6-oxo-1,6-dihydro-3-pyridinecarboxamide

反応式

[CH2:25]([C:26]#[CH:27])[OH:28].[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[Cu:39][I:40].[F:1][c:2]1[c:3]([NH:4][c:5]2[c:6]([C:13](=[O:14])[NH:15][CH2:16][CH2:17][CH2:18][OH:19])[cH:7][n:8]([CH3:12])[c:9](=[O:11])[cH:10]2)[cH:20][cH:21][c:22]([I:24])[cH:23]1.[O:34]=[CH:35][N:36]([CH3:37])[CH3:38]>>[F:1][c:2]1[c:3]([NH:4][c:5]2[c:6]([C:13](=[O:14])[NH:15][CH2:16][CH2:17][CH2:18][OH:19])[cH:7][n:8]([CH3:12])[c:9](=[O:11])[cH:10]2)[cH:20][cH:21][c:22]([C:27]#[C:26][CH2:25][OH:28])[cH:23]1