Acetate → Tert-butyl 4-(3-cyclopropyl-2-fluorobenzoyl)piperazine-1-carboxylate
反応式
[Br:1][c:2]1[c:3]([F:23])[c:4]([C:5](=[O:6])[N:7]2[CH2:8][CH2:9][N:10]([C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[CH2:11][CH2:12]2)[cH:20][cH:21][cH:22]1.[C:65]([O-:66])(=[O:67])[CH3:68].[C:70]([O-:71])(=[O:72])[CH3:73].[CH3:57][c:58]1[cH:59][cH:60][cH:61][cH:62][cH:63]1.[CH:24]1([B:27]([OH:28])[OH:29])[CH2:25][CH2:26]1.[CH:30]1([P:31]([CH:32]2[CH2:33][CH2:34][CH2:35][CH2:36][CH2:37]2)[CH:38]2[CH2:39][CH2:40][CH2:41][CH2:42][CH2:43]2)[CH2:44][CH2:45][CH2:46][CH2:47][CH2:48]1.[K+:54].[K+:55].[K+:56].[OH2:64].[P:49]([O-:50])([O-:51])([O-:52])=[O:53].[Pd+2:69]>>[c:2]1([CH:24]2[CH2:25][CH2:26]2)[c:3]([F:23])[c:4]([C:5](=[O:6])[N:7]2[CH2:8][CH2:9][N:10]([C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[CH2:11][CH2:12]2)[cH:20][cH:21][cH:22]1
