HCID 58577747、化合物 → 4-(2,3-dihydro-1H-imidazo[2',1':2,3]imidazo[4,5-b]pyridin-1-yl)aniline
反応式
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[C:14]3=[N:15][C:16]4[C:17](=[N:18][CH:19]=[CH:20][CH:21]=4)[N:13]3[CH2:12][CH2:11]2)=[CH:6][CH:5]=1)([O-])=O>[Pd].CO>[N:10]1([C:7]2[CH:6]=[CH:5][C:4]([NH2:1])=[CH:9][CH:8]=2)[C:14]2=[N:15][C:16]3[C:17](=[N:18][CH:19]=[CH:20][CH:21]=3)[N:13]2[CH2:12][CH2:11]1参加物
4
実験手順
A mixture of 1-(4-nitrophenyl)-2,3-dihydro-1H-imidazo[2′,1′:2,3]imidazo[4,5-b]pyridine (1.7 g) and 10% palladium on carbon (50% wet, 1.0 g) in MeOH (150 ml) was hydrogenated under balloon pressure at room temperature for 1 day. The catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to give the title compound (1.2 g).
後処理
- customThe catalyst was removed by filtration
- concentrationthe filtrate was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-fd203bc0c94044c086aec828f15044b4
- 出典データセット
- uspto-grants-2014_09
- 特許番号
- US08846713B2
反応ノート
読み込み中…