Dimethylformamide → 4-amino-2-fluoro-5-methoxy-N-[[1-(pyrrolidin-1-ylmethyl)cyclopropyl]methyl]benzamide

反応式

[CH:49]([N:50]([CH2:51][CH3:52])[CH:53]([CH3:54])[CH3:55])([CH3:56])[CH3:57].[N:14]1([CH2:19][C:20]2([CH2:23][NH2:24])[CH2:21][CH2:22]2)[CH2:15][CH2:16][CH2:17][CH2:18]1.[NH2:1][c:2]1[cH:3][c:4]([F:13])[c:5]([C:6](=[O:7])[OH:8])[cH:9][c:10]1[O:11][CH3:12].[O:58]=[CH:59][N:60]([CH3:61])[CH3:62].[P-:25]([F:26])([F:27])([F:28])([F:29])([F:30])[F:31].[n:32]1([O:33][C:34]([N:35]([CH3:36])[CH3:37])=[N+:38]([CH3:39])[CH3:40])[c:41]2[n:42][cH:43][cH:44][cH:45][c:46]2[n:47][n:48]1>>[NH2:1][c:2]1[cH:3][c:4]([F:13])[c:5]([C:6](=[O:8])[NH:24][CH2:23][C:20]2([CH2:19][N:14]3[CH2:15][CH2:16][CH2:17][CH2:18]3)[CH2:21][CH2:22]2)[cH:9][c:10]1[O:11][CH3:12]