Pyridine → 1-(4-Chloro-5-(1-ethyl-7-(1-methylpyrrolidin-3-ylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl)-3-phenylurea

反応式

[Cl:45][CH2:46][Cl:47].[NH2:1][c:2]1[c:3]([F:29])[cH:4][c:5]([Cl:28])[c:6](-[c:8]2[c:9](=[O:27])[n:10]([CH2:25][CH3:26])[c:11]3[cH:12][c:13]([NH:18][CH:19]4[CH2:20][N:21]([CH3:24])[CH2:22][CH2:23]4)[n:14][cH:15][c:16]3[cH:17]2)[cH:7]1.[O:36]=[C:37]=[N:38][c:39]1[cH:40][cH:41][cH:42][cH:43][cH:44]1.[cH:30]1[cH:31][cH:32][n:33][cH:34][cH:35]1>>[NH:1]([c:2]1[c:3]([F:29])[cH:4][c:5]([Cl:28])[c:6](-[c:8]2[c:9](=[O:27])[n:10]([CH2:25][CH3:26])[c:11]3[cH:12][c:13]([NH:18][CH:19]4[CH2:20][N:21]([CH3:24])[CH2:22][CH2:23]4)[n:14][cH:15][c:16]3[cH:17]2)[cH:7]1)[C:37](=[O:36])[NH:38][c:39]1[cH:40][cH:41][cH:42][cH:43][cH:44]1