Methanol → (R)-(+)-3,7-dimethyloctanoic acid
反応式
C([O:3][C:4](=[O:14])[CH2:5][C@H:6]([CH3:13])[CH2:7][CH2:8][CH2:9][CH:10]([CH3:12])[CH3:11])C.CO>[OH-].[Na+]>[CH3:13][C@H:6]([CH2:7][CH2:8][CH2:9][CH:10]([CH3:12])[CH3:11])[CH2:5][C:4]([OH:14])=[O:3]参加物
4
実験手順
300 mg. of 3(R),7-dimethyl octanoic acid ethyl ester obtained from example 14 was refluxed in 6N NaOH (1 ml.), methanol (4 ml.) for 2 hours. It was worked up as in Example 10 to give 226 mg. (87.5% yield) of R-(+)-dihydrocitronellic acid, b.p. 54°/0.4 mmHg. (Kugelrohr), [α]D25 + 6.31° (c=5.069, CHCl3).
後処理
- customto give 226 mg
出典と根拠
- ORDレコード
- ord-9bf115a216fa4a0c84196a66c55865da
- 出典データセット
- uspto-grants-1978_06
- 特許番号
- US04094892
反応ノート
読み込み中…