1-Acetylcyclopentene → 2,3,4,4a,6,7,11b,12,13,13a-decahydro-9,10-dimethoxy-1H-dibenzo[a,f]quinolizin-13-one

HRID 839511

反応式

HRID 839511 の反応式
Cl.[CH3:2][O:3][C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][C:13]=1[O:14][CH3:15])[CH:10]=[N:9][CH2:8][CH2:7]2.Cl.C1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH2:20][CH2:19]N=1.CC(C1CCCC=1)=[O:29]>CC(C)=O>[CH3:2][O:3][C:4]1[C:13]([O:14][CH3:15])=[CH:12][C:11]2[CH:10]3[N:9]([CH2:8][CH2:7][C:6]=2[CH:5]=1)[CH:22]1[CH2:23][CH2:24][CH2:25][CH2:26][CH:21]1[C:20](=[O:29])[CH2:19]3

参加物

5

反応物 3

HCID 1929251-AcetylcyclopenteneHCID 27246643,4-Dihydro-6,7-dimethoxyisoquinoline hydrochlorideHCID 204638553,4-Dihydroisoquinoline--hydrogen chloride (1/1)

生成物 1

HCID 127744922,3,4,4a,6,7,11b,12,13,13a-decahydro-9,10-dimethoxy-1H-dibenzo[a,f]quinolizin-13-one

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

When in Example 32 appropriate amounts of 3,4-dihydro-6,7-dimethoxyisoquinoline hydrochloride and 1-chylohexen-1-yl methyl ketone respectively are substituted for 3,4-dihydroisoquinoline hydrochloride and 1-cyclopenten-1-yl methyl ketone, 2,3,4,4a,6,7,11b,12,13,13a-decahydro-9,10-dimethoxy-1H-dibenzo[a,f]quinolizin-13-one is obtained M.P. 129°-141° C.

出典と根拠

ORDレコード
ord-93740712527c4945a4bce8294a5728ce
出典データセット
uspto-grants-1978_06
特許番号
US04096147

関連ノート

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