Hydrochloric Acid → Ethyl-m-[N,N-di(n-hexadecyl)aminomethyl]-benzimidate dihydrochloride

HRID 839897

反応式

HRID 839897 の反応式
[CH2:1]([N:17]([CH2:34][C:35]1[CH:40]=[CH:39][CH:38]=[C:37]([C:41]#[N:42])[CH:36]=1)[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[O:43]1CCO[CH2:45][CH2:44]1.[ClH:49]>C(O)C.C1C=CC=CC=1>[ClH:49].[ClH:49].[CH2:44]([O:43][C:41](=[NH:42])[C:37]1[CH:38]=[CH:39][CH:40]=[C:35]([CH2:34][N:17]([CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])[CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[CH:36]=1)[CH3:45]

参加物

6

反応物 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 125651361-(Dihexadecyl)aminomethyl-3-cyanobenzene

生成物 1

HCID 70618744Ethyl-m-[N,N-di(n-hexadecyl)aminomethyl]-benzimidate dihydrochloride収率 100%

試薬・触媒・溶媒 2

HCID 241Benzene溶媒HCID 702Ethanol溶媒2 回

実験手順

A mixture of α-[N,N-di(n-hexadecyl)amino]-m-toluonitrile (29.0 g., 0.05 mole), ethanol (40 ml., 0.67 mole) and dioxane (100 ml.) was saturated with dry hydrogen chloride gas for 40 minutes at 15°-25° C. It was then stoppered and held overnight at room temperature. Thin layer chromatography analysis (4:1, benzene:ethanol on silica gel) indicated complete reaction of the nitrile. The mixture was evaporated in vacuo yielding the named product quantitatively as a foam [35.0 g., ~ 100% yield, Rf .87 (4:1, benzene: ethanol on silica gel)].

後処理

  1. customThe mixture was evaporated in vacuo
  2. customyielding the named product quantitatively as a foam [35.0 g., ~ 100% yield, Rf .87 (4:1, benzene: ethanol on silica gel)]

出典と根拠

ORDレコード
ord-2279aa780a0e4ceda68453f25aaca4d6
出典データセット
uspto-grants-1978_06
特許番号
US04097525

関連ノート

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