Hydrochloric Acid → HCID 15406934、化合物
反応式
[CH3:1][C:2]([C:9]1[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=1)([CH3:8])[C:3]([O:5]CC)=[O:4].[Li+].[OH-].O.Cl>CCO>[CH3:8][C:2]([C:9]1[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=1)([CH3:1])[C:3]([OH:5])=[O:4]参加物
6
反応条件
- 温度
- 25 °C
実験手順
Ethyl α,α-dimethyl-3-pyridylacetate (disclosed in EP application 0 288 279, published Oct. 26, 1988) (2.67 grams, 13.8 mmoles) was dissolved in EtOH (11.1 ml.) and a 1.0M LiOH in water (33.3 ml.) (33.4 mmoles) was added. The mixture was stirred at 25° C. for 4 hours. 1 N HCl (38.73 ml.) was added and after 5 minutes the mixture was evaporated to dryness to give the title compound (Yield: 100%).
後処理
- customwas evaporated to dryness
出典と根拠
- ORDレコード
- ord-276d83f8d5c246c888e8357864494c2c
- 出典データセット
- uspto-grants-2002_04
- 特許番号
- US06365588B1
反応ノート
読み込み中…