Phthalic Anhydride → 3-[(3-Methoxyphenyl)methylidene]-2-benzofuran-1(3H)-one
反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:9][C:10]([OH:12])=O)[CH:6]=[CH:7][CH:8]=1.C1(=O)O[C:16](=[O:17])[C:15]2=[CH:19][CH:20]=[CH:21][CH:22]=[C:14]12>C([O-])(=O)C.[Na+]>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:6]=[CH:7][CH:8]=1)[CH:9]=[C:10]1[C:19]2[C:15](=[CH:14][CH:22]=[CH:21][CH:20]=2)[C:16](=[O:17])[O:12]1参加物
4
反応条件
- 温度
- 240 °C
実験手順
A mixture of 15 g (89 mmol) of m-methoxyphenyl acetic acid, 13.2 g (89 mmol) of phthalic anhydride and 246 mg (2.9 mmol) of sodium acetate was heated to 240° C. for 6 hours and water was continuously removed from the reaction. The solid formed in the reaction flask on cooling. This was recrystallized from absolute ethanol to obtain 15.6 g (62 mmol, 69%) of 1 as yellow powder.