Hydrogen Bromide → 1-Bromo-3,7-dimethyloctane

HRID 84062

反応式

HRID 84062 の反応式
S(=O)(=O)(O)O.[CH3:6][CH:7]([CH2:11][CH2:12][CH2:13][CH:14]([CH3:16])[CH3:15])[CH2:8][CH2:9]O.[BrH:17]>>[CH3:6][CH:7]([CH2:11][CH2:12][CH2:13][CH:14]([CH3:16])[CH3:15])[CH2:8][CH2:9][Br:17]

参加物

4

反応物 3

HCID 260Hydrogen BromideHCID 1118Sulfuric AcidHCID 77923,7-Dimethyl-1-octanol

生成物 1

HCID 1379141-Bromo-3,7-dimethyloctane収率 82.1%

実験手順

48% HBr (200 ml) and concentrated sulfuric acid (0.46 ml) were added to 3,7-dimethyl-1-octanol (21.0 g, 157.9 mmol), and the mixture was heated overnight. After allowing to cool to room temperature, and the mixture was extracted with hexane. The organic layer was washed with 5% aqueous sodium hydrogen carbonate solution and saturated brine, dried and concentrated to give the title compound (28.7 g, 82.1%).

後処理

  1. temperaturethe mixture was heated overnight
  2. extractionthe mixture was extracted with hexane
  3. washThe organic layer was washed with 5% aqueous sodium hydrogen carbonate solution and saturated brine
  4. customdried
  5. concentrationconcentrated

出典と根拠

ORDレコード
ord-68ffd444f96c4333a3dda341ab53f8fc
出典データセット
uspto-grants-2014_09
特許番号
US08846885B2

関連ノート

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