9,9-Dichloro-9-silafluorene → 4-(3',5'-Di-t-butylphenyl)-2-methylindene

HRID 843194ノート

反応式

HRID 843194 の反応式
Cl[Si]1(Cl)C2C=CC=CC=2C2C1=CC=CC=2.[C:16]([C:20]1[CH:21]=[C:22]([C:30]2[CH:38]=[CH:37][CH:36]=[C:35]3[C:31]=2[CH:32]=[C:33]([CH3:39])[CH2:34]3)[CH:23]=[C:24]([C:26]([CH3:29])([CH3:28])[CH3:27])[CH:25]=1)([CH3:19])([CH3:18])[CH3:17].[Li]>C1COCC1>[C:16]([C:20]1[CH:21]=[C:22]([C:30]2[CH:38]=[CH:37][CH:36]=[C:35]3[C:31]=2[CH:32]=[C:33]([CH3:39])[CH2:34]3)[CH:23]=[C:24]([C:26]([CH3:29])([CH3:28])[CH3:27])[CH:25]=1)([CH3:17])([CH3:18])[CH3:19]

参加物

4

反応物 2

HCID 6195839,9-Dichloro-9-silafluoreneHCID 69684158Lithium 4(3',5'-di-t-butylphenyl)-2-methylindene

生成物 1

HCID 120107434-(3',5'-Di-t-butylphenyl)-2-methylindene

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

9,9-Dichloro-9-silafluorene (1.2 g, 9.2 mmol) was dissolved in 80 mL of THF. To this solution was slowly added lithium 4-(3′,5′-di-t-butylphenyl)-2-methylindene (3.0 g, 9.2 mmol) as a dry powder and the solution was stirred overnight. After this time, the solvent was removed in vacuo and the residue was taken up in diethyl ether. The solution was filtered through a frit to remove LiCl and the solvent was removed in vacuo and used as a crude product (4.1 g) for the next step.

後処理

  1. customAfter this time, the solvent was removed in vacuo
  2. filtrationThe solution was filtered through a frit
  3. customto remove LiCl
  4. customthe solvent was removed in vacuo

出典と根拠

ORDレコード
ord-1cb33b7c87104b8e9d1a4a21a1f5e253
出典データセット
uspto-grants-2002_04
特許番号
US06376627B1

反応ノート

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