Methyl iodide → 1-(3,5-Difluoro-2-methoxyphenyl)ethanone

反応式

[CH3:1]I.[F:3][C:4]1[C:5]([OH:14])=[C:6]([C:11](=[O:13])[CH3:12])[CH:7]=[C:8]([F:10])[CH:9]=1>>[F:3][C:4]1[C:5]([O:14][CH3:1])=[C:6]([C:11](=[O:13])[CH3:12])[CH:7]=[C:8]([F:10])[CH:9]=1

参加物

反応物 2

HCID 6328Methyl iodide

HCID 27369761-(3,5-Difluoro-2-hydroxyphenyl)ethan-1-one

生成物 1

HCID 187554401-(3,5-Difluoro-2-methoxyphenyl)ethanone

実験手順

In an analogous manner to that described in (α) 1-(3,5-difluoro-2-hydroxy-phenyl)-ethanone was alkylated with methyliodide to yield 1-(3,5-difluoro-2-methoxy-phenyl)-ethanone as beige needles; MS: 186 (M)+.

出典と根拠

ORDレコード: ord-e1f89bd63c74452eaaf77d56c6f7abf1
出典データセット: uspto-grants-2002_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06376672B1

反応ノート

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