HCID 22612300、化合物 → 3-(1H-tetrazol-1-yl)phenol

HRID 843987ノート

反応式

HRID 843987 の反応式
C([O:8][C:9]1[CH:10]=[C:11]([N:15]2[CH:19]=[N:18][N:17]=[N:16]2)[CH:12]=[CH:13][CH:14]=1)C1C=CC=CC=1>C(O)C.[Pd]>[N:15]1([C:11]2[CH:10]=[C:9]([OH:8])[CH:14]=[CH:13][CH:12]=2)[CH:19]=[N:18][N:17]=[N:16]1

参加物

4

反応物 1

HCID 22612300HCID 22612300、化合物

生成物 1

HCID 8561923-(1H-tetrazol-1-yl)phenol収率 88.4%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

To a solution 1-(3-Benzyloxy-phenyl)-1H-tetrazole (0.640 grams, 2.54 mmole) in ethanol (15 ml) was added 10% palladium on carbon (˜0.100 g). This was stirred under hydrogen balloon over night. The catalyst was removed by filtration, and the solution was concentrated to give a white solid (0.364 g). M.P. 171-172° C.; MW 162.12; MS (m/e) 163 (M++1).

後処理

  1. customThe catalyst was removed by filtration
  2. concentrationthe solution was concentrated

出典と根拠

ORDレコード
ord-7cee0a2b5c1d42d6a4a23305cd52ffdb
出典データセット
uspto-grants-2002_04
特許番号
US06380218B1

反応ノート

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