Sulfuric Acid → HCID 15538329、化合物
反応式
[CH3:1][N:2]([CH3:10])[CH2:3][CH2:4][N:5]([CH3:9])[CH2:6][CH2:7][OH:8].[H-].[Na+].[C:13]([NH2:17])(=[O:16])[CH:14]=[CH2:15].S(=O)(=O)(O)O>>[CH3:1][N:2]([CH3:10])[CH2:3][CH2:4][N:5]([CH3:9])[CH2:6][CH2:7][O:8][CH2:15][CH2:14][C:13]([NH2:17])=[O:16]参加物
5
実験手順
A 50 ml 3 neck round bottom flask was fitted with the following: magnetic stirrer, reflux condenser, air bubbler, and a temperature controlled oil bath. The flask was charged with 7.3 g of 2-{[2-(dimethylamino)ethyl]methylamino}ethanol. Sodium hydride, 0.014 g, was then added carefully to the of 2-{[2-(dimethylamino)ethyl]methylamino}ethanol with stirring. The mixture was stirred at a constant rate for two minutes before 3.55 g of acrylamide was added. After the addition of acrylamide, the reaction mixture was stirred at 50° C. for 6 hours. The mixture was cooled to ambient temperature. Concentrated sulfuric acid, 0.034 g, then was added to neutralize the product mixture. The resulting mixture was filtered through a Celite layer. The filtrate was collected for foam application. Quantitative 1H NMR showed that the product was 94% pure.