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Dicyclohexylcarbodiimide → HCID 178444583、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dicyclohexylcarbodiimide | HCID 10868 | — |
| 反応物 | 3-Fluoro-4-(trans-5-pentyl-1,4-dioxane-2-yl)benzoic acid | HCID 70418790 | — |
| 反応物 | HCID 178448131 | HCID 178448131 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | HCID 178444583 | HCID 178444583 | — |
反応手順
A mixture of 2.96 g. 3-fluoro-4-(trans-5-pentyl-1,4-dioxane-2-yl)benzoic acid (obtainable from the nitrile, cf. Example 7), 1.42 g. trans-4-propylcyclohexanol and 2.06 g. dicyclohexylcarbodiimide is boiled in 50 ml. diethyl ether for 6 hours. After cooling, one filters, works up as usual and obtains 3-fluoro-4-(trans-5-pentyl-1,4-dioxan-2-yl)benzoic acid trans-4-propylcyclohexyl ester.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04755323 |
| 出典データセット | uspto-grants-1988_07 |
| ORD ID | ord-8b1b3fb6d0144c3281dfc164d31e6520 |
| 出典メモ | uspto-grants-1988_07 |