HCID 19014057、化合物 → HCID 19014054、化合物
反応式
C([CH:5]([C:17]([OH:19])=[O:18])[O:6][C:7]1[CH:8]=[C:9]([CH2:13][C:14](=[O:16])[CH3:15])[CH:10]=[CH:11][CH:12]=1)(C)(C)C>FC(F)(F)C(O)=O>[C:17]([CH2:5][O:6][C:7]1[CH:8]=[C:9]([CH2:13][C:14](=[O:16])[CH3:15])[CH:10]=[CH:11][CH:12]=1)([OH:19])=[O:18]参加物
3
実験手順
To m-(t-butylcarboxymethoxy)phenyl acetone, 6.7 g, was added trifluoroacetic acid (40 ml) at room temperature under nitrogen. After five minutes, reaction was found to be completed by tlc (silica gel eluted with 1:9 parts by volume methanol:methylene chloride) and the solvent was then evaporated to dryness. The resulting brown oil showed the desired product and trace of starting material on tlc. IR showed characteristic carboxylic acid peak at 3600-2450 cm-1.
後処理
- customreaction
- washto be completed by tlc (silica gel eluted with 1:9 parts by volume methanol:methylene chloride)
- customthe solvent was then evaporated to dryness
出典と根拠
- ORDレコード
- ord-42c009f3d0b44032b09f074e36fbecbc
- 出典データセット
- uspto-grants-1992_08
- 特許番号
- US05135863
反応ノート
読み込み中…