4-Hydroxybenzaldehyde → 2-(Hexyloxy)benzaldehyde
反応式
CN([CH:4]=[O:5])C.C(=O)([O-])[O-].[K+].[K+].[OH:12][C:13]1[CH:20]=[CH:19][C:16](C=O)=[CH:15][CH:14]=1.[CH2:21](Br)[CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]>O>[CH2:21]([O:12][C:13]1[CH:14]=[CH:15][CH:16]=[CH:19][C:20]=1[CH:4]=[O:5])[CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]参加物
6
実験手順
To 250 ml of DMF containing 207 g of anhydrous potassium carbonate (1.5M) was added 122 g of 4-hydroxybenzaldehyde and 181.6 g of hexylbromide. The resultant mixture was heated at reflux temperature overnight after which it was poured into cold water and extracted with ethylacetate. The extracts were dried and evaporated in vacuo to afford the desired subtitled intermediate (80% yield), b.p. 110°-115° C.
後処理
- temperatureat reflux temperature overnight after which it
- extractionextracted with ethylacetate
- customThe extracts were dried
- customevaporated in vacuo
出典と根拠
- ORDレコード
- ord-15d173bb53d647d288e8eb7dc4418afe
- 出典データセット
- uspto-grants-1992_08
- 特許番号
- US05135955
反応ノート
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