Methyl iodide → 4-Methyl-3-nitroanisole

反応式

[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].[C:12](=O)([O-])[O-].[K+].[K+].CI>>[CH3:12][O:8][C:5]1[CH:6]=[CH:7][C:2]([CH3:1])=[C:3]([N+:9]([O-:11])=[O:10])[CH:4]=1

参加物

反応物 3

HCID 6328Methyl iodide

HCID 11430Potassium Carbonate

HCID 162713-Nitro-p-cresol

生成物 1

HCID 871374-Methyl-3-nitroanisole収率 97.5%

実験手順

In the manner of Example 8, Step C, the reaction of 25.0 g (0.162 mole) of 4-methyl-3-nitrophenol, 23.3 g (0.168 mole) of potassium carbonate, and 34.1 9 (0.24 mole) of methyl iodide produced 26.4 g of 1-methoxy-4-methyl-3-nitrobenzene as an oil.

出典と根拠

ORDレコード: ord-f6464f96dad34604b0156565e6c576fd
出典データセット: uspto-grants-1992_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05136868

反応ノート

読み込み中…