Morpholine → HCID 19883113、化合物
反応式
[F:1][C:2]1[N:7]=[C:6]([S:8](Cl)(=[O:10])=[O:9])[CH:5]=[CH:4][CH:3]=1.[NH:12]1[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1>C(Cl)(Cl)Cl>[N:12]1([S:8]([C:6]2[CH:5]=[CH:4][CH:3]=[C:2]([F:1])[N:7]=2)(=[O:10])=[O:9])[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1参加物
4
実験手順
To a solution of 6-fluoropyridine-2-sulphonyl chloride (1.96 g) in chloroform (40 cm3) at 0° C. was added a solution of morpholine (1.74 g) in chloroform (20 cm3). The reaction was quenched in water (100 cm3) and the product extracted into chloroform (3×50 cm3). The combined organic layers were washed with water, dried over anhydrous magnesium sulphate and the solvent evaporated under reduced pressure to give the title compound which was used without further purification.
後処理
- customThe reaction was quenched in water (100 cm3)
- extractionthe product extracted into chloroform (3×50 cm3)
- washThe combined organic layers were washed with water
- dry with materialdried over anhydrous magnesium sulphate
- customthe solvent evaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-ef7be755cc6f4a20b3d82e71de298a66
- 出典データセット
- uspto-grants-1992_08
- 特許番号
- US05137886
反応ノート
読み込み中…