3,3-Dimethoxy-pyrrolidine benzyl carbamate → 3,3-Dimethoxypyrrolidine

HRID 846687

反応式

HRID 846687 の反応式
C(NC(=O)O)C1C=CC=CC=1.[CH3:12][O:13][C:14]1([O:19][CH3:20])[CH2:18][CH2:17][NH:16][CH2:15]1.[H][H]>CO.[Pd]>[CH3:12][O:13][C:14]1([O:19][CH3:20])[CH2:18][CH2:17][NH:16][CH2:15]1

参加物

5

反応物 2

HCID 867460613,3-Dimethoxy-pyrrolidine benzyl carbamateHCID 178418361HCID 178418361、化合物

生成物 1

HCID 110298823,3-Dimethoxypyrrolidine

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

The 2.21 g of 3,3-dimethoxy-pyrrolidine benzyl carbamate, from step 3, dissolved in 100 mL of methanol, 2.21 g of Pd/C (wet) was added, and placed under 4 atm of hydrogen for 20 hours. The catalyst was filtered off using a 0.45 micro millipore filter and the solvent was evaporated to afford the title compound.

後処理

  1. filtrationThe catalyst was filtered off
  2. filtrationfilter
  3. customthe solvent was evaporated

出典と根拠

ORDレコード
ord-8db8cb3449b64d54a778053f320dfcbb
出典データセット
uspto-grants-1992_08
特許番号
US05137892

関連ノート

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