4-((Dimethylamino)methyl)benzonitrile → HCID 19881402、化合物

HRID 847414ノート

反応式

HRID 847414 の反応式
[CH:1]1[C:18]2[C:5](=[C:6]([C:19]3[CH:26]=[CH:25][CH:24]=[CH:23][C:20]=3[CH2:21][Br:22])[C:7]3[C:16]([CH:17]=2)=[CH:15][C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:8]=3)[CH:4]=[CH:3][CH:2]=1.[CH3:27][N:28]([CH2:30][C:31]1[CH:36]=[CH:35][C:34]([C:37]#[N:38])=[CH:33][CH:32]=1)[CH3:29].[PH4+].[AsH4+]>C(#N)C.C(OCC)C>[Br-:22].[C:37]([C:34]1[CH:33]=[CH:32][C:31]([CH2:30][N+:28]([CH2:21][C:20]2[CH:23]=[CH:24][CH:25]=[CH:26][C:19]=2[C:6]2[C:7]3[C:16](=[CH:15][C:14]4[C:9]([CH:8]=3)=[CH:10][CH:11]=[CH:12][CH:13]=4)[CH:17]=[C:18]3[C:5]=2[CH:4]=[CH:3][CH:2]=[CH:1]3)([CH3:27])[CH3:29])=[CH:36][CH:35]=1)#[N:38]

参加物

7

反応物 4

HCID 8263294-((Dimethylamino)methyl)benzonitrileHCID 5460504PhosphoniumHCID 5460506ArsoniumHCID 19881404HCID 19881404、化合物

生成物 1

HCID 19881402HCID 19881402、化合物

試薬・触媒・溶媒 2

HCID 3283Diethyl Ether溶媒HCID 6342Acetonitrile溶媒

実験手順

A mixture of (B) and N,N-dimethyl-4-cyano benzylamine in acetonitrile was refluxed for 2 hours. The reaction mixture was then poured into diethyl ether, and the crude product was collected by filtration. The crude product was recrystallized from ethanol. The same reaction can be used to prepare the corresponding phosphonium and arsonium salts.

後処理

  1. temperaturewas refluxed for 2 hours
  2. filtrationthe crude product was collected by filtration
  3. customThe crude product was recrystallized from ethanol
  4. customThe same reaction

出典と根拠

ORDレコード
ord-c99f46cb7eb8477eb0e8a2917d7c6568
出典データセット
uspto-grants-1992_08
特許番号
US05141969

反応ノート

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