3-n-Butyl-5-(2,4,5-trimethoxybenzylidene) hydantoin → 3-n-Butyl-5-(2,4,5-trimethoxybenzyl) hydantoin
反応式
[CH2:1]([N:5]1[C:9](=[O:10])[C:8](=[CH:11][C:12]2[CH:17]=[C:16]([O:18][CH3:19])[C:15]([O:20][CH3:21])=[CH:14][C:13]=2[O:22][CH3:23])[NH:7][C:6]1=[O:24])[CH2:2][CH2:3][CH3:4]>[Pd].C(O)(=O)C>[CH2:1]([N:5]1[C:9](=[O:10])[CH:8]([CH2:11][C:12]2[CH:17]=[C:16]([O:18][CH3:19])[C:15]([O:20][CH3:21])=[CH:14][C:13]=2[O:22][CH3:23])[NH:7][C:6]1=[O:24])[CH2:2][CH2:3][CH3:4]参加物
4
実験手順
3-n-Butyl-5-(2,4,5-trimethoxybenzylidene) hydantoin (10.0 g; 0.03 mole) was mixed with glacial acetic acid (150 ml.) and hydrogenated in a Parr apparatus in the presence of 5% Pd/C (2 g). After 2 hours the catalyst was filtered off, washed with warm acetic acid and the colourless filtrate evaporated in vacuo to give a white crystalline solid. Recrystallisation from ethyl acetate gave the title compound, yield 9.2 g (91% ), m.p. 122° C.