Ethyl chloroformate → HCID 20566350、化合物

HRID 848171ノート

反応式

HRID 848171 の反応式
Cl[C:2]([O:4][CH2:5][CH3:6])=[O:3].[NH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[S:14][CH2:15][C:16]1[N:20]=[CH:19][O:18][N:17]=1>C1C=CC=CC=1>[CH2:5]([O:4][C:2]([NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[S:14][CH2:15][C:16]1[N:20]=[CH:19][O:18][N:17]=1)=[O:3])[CH3:6]

参加物

4

反応物 2

HCID 10928Ethyl chloroformateHCID 3057622Benzenamine, 2-((1,2,4-oxadiazol-3-ylmethyl)thio)-

生成物 1

HCID 20566350HCID 20566350、化合物

試薬・触媒・溶媒 1

HCID 241Benzene溶媒2 回

実験手順

A solution of ethyl chloroformate (0.55 g) in benzene (10 ml) was added dropwise to a solution of 3-(2-aminophenylthiomethyl)-1,2,4-oxadiazole (2.07 g) in benzene (10 ml). The reaction mixture was then stirred for 2 days, filtered and the filtrate evaporated under reduced pressure to give an oil which crystallised on standing. Re-crystallisation from isopropanol gave 3-(2-ethoxycarbonylaminophenylthiomethyl)-1,2,4-oxadiazole, m.p. 55°.

後処理

  1. filtrationfiltered
  2. customthe filtrate evaporated under reduced pressure
  3. customto give an oil which
  4. customcrystallised

出典と根拠

ORDレコード
ord-c2b1806fbbdb457392ca9e5d57664cd3
出典データセット
uspto-grants-1981_10
特許番号
US04294843

反応ノート

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