Water → HCID 20566347、化合物

HRID 848174ノート

反応式

HRID 848174 の反応式
[CH3:1][S:2](Cl)(=[O:4])=[O:3].[NH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[S:13][CH2:14][C:15]1[N:19]=[CH:18][O:17][N:16]=1.O>N1C=CC=CC=1>[CH3:1][S:2]([NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[S:13][CH2:14][C:15]1[N:19]=[CH:18][O:17][N:16]=1)(=[O:4])=[O:3]

参加物

5

反応物 3

HCID 962WaterHCID 31297Methanesulfonyl chlorideHCID 3057622Benzenamine, 2-((1,2,4-oxadiazol-3-ylmethyl)thio)-

生成物 1

HCID 20566347HCID 20566347、化合物

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

Methanesulphonyl chloride (1.39 g) was added dropwise to a cooled solution of 3-(2-aminophenylthiomethyl)-1,2,4-oxadiazole (3.1 g) in pyridine (12 ml). The reaction mixture was then poured into water (75 ml) the so formed solid removed by filtration and crystallised from ethanol to give 3-(2-methylsulphonamidophenylthiomethyl)-1,2,4-oxadiazole, m.p. 106°.

後処理

  1. customremoved by filtration
  2. customcrystallised from ethanol

出典と根拠

ORDレコード
ord-7d0737f2ea4f42e69f5b2de7e77e5887
出典データセット
uspto-grants-1981_10
特許番号
US04294843

反応ノート

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