2-(Dimethylamino)ethanol → N,N1-Dimethyl-S-(2-dimethylaminoethyl)isothiourea
反応式
[CH3:1][N:2]([CH3:6])[CH2:3][CH2:4]O.[CH3:7][N:8]([CH3:12])[C:9]([NH2:11])=[S:10]>Br>[CH3:7][N:8]([CH3:12])[C:9](=[NH:11])[S:10][CH2:4][CH2:3][N:2]([CH3:6])[CH3:1]参加物
4
実験手順
A mixture of 2-dimethylaminoethanol (2.23 g), N,N1 -dimethylthiourea (2.6 g) and aqueous hydrobromic acid (48%, 20 ml) was boiled under reflux for 50 hours and evaporated to dryness. The residue was recrystallised from a mixture of methanol and ethanol to give the dihydrobromide of the title compound (5.6 g) m.p. 198°-199°.
後処理
- temperatureunder reflux for 50 hours
- customevaporated to dryness
- customThe residue was recrystallised from a mixture of methanol and ethanol
出典と根拠
- ORDレコード
- ord-63d179611f024bd1ad2279dc64a1524d
- 出典データセット
- uspto-grants-1981_10
- 特許番号
- US04294854
反応ノート
読み込み中…