Isopropylamine → bis(N-(propan-2-yl)guanidine); sulfuric acid

HRID 848806

反応式

HRID 848806 の反応式
[S:1]([OH:5])([OH:4])(=[O:3])=[O:2].CS[C:8](=[NH:10])[NH2:9].CS[C:13](=[NH:15])[NH2:14].[CH:16]([NH2:19])([CH3:18])[CH3:17]>O>[S:1]([OH:5])([OH:4])(=[O:3])=[O:2].[CH:16]([NH:19][C:8]([NH2:10])=[NH:9])([CH3:18])[CH3:17].[CH:16]([NH:19][C:13]([NH2:15])=[NH:14])([CH3:18])[CH3:17]

参加物

4

反応物 2

HCID 6363IsopropylamineHCID 13347Bis(S-methylisothiouronium) sulfate

生成物 1

HCID 178457583bis(N-(propan-2-yl)guanidine); sulfuric acid収率 82%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

Into a one liter reactor fitted with warming, cooling and stirring means were poured 108.5 g (0.39 mol) of bis (S-methylisothiourea) sulphate, 150 ml of water and 94 ml (or 68 g, i.e. 1.15 mol) of isopropylamine. The mixture was refluxed for two hours and then evaporated to dryness. The residue was taken up in ethanol from which there was obtained, after filtration, washing and drying, 96 g (yield 82%) of product.

後処理

  1. customInto a one liter reactor fitted
  2. temperaturewith warming
  3. temperaturecooling
  4. temperatureThe mixture was refluxed for two hours
  5. customevaporated to dryness
  6. customwas obtained
  7. filtrationafter filtration
  8. washwashing
  9. customdrying

出典と根拠

ORDレコード
ord-f8f9f993b4ff4d818258ff8143a1a356
出典データセット
uspto-grants-1981_10
特許番号
US04297495

関連ノート

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