Hydrochloric Acid → 1-Aminocyclopentane-1-carboxamide hydrochloride

HRID 84919

反応式

HRID 84919 の反応式
[C:1]([C:4]1([NH:9]C(=O)OC(C)(C)C)[CH2:8][CH2:7][CH2:6][CH2:5]1)(=[O:3])[NH2:2].[ClH:17]>O1CCOCC1>[ClH:17].[NH2:9][C:4]1([C:1]([NH2:2])=[O:3])[CH2:8][CH2:7][CH2:6][CH2:5]1

参加物

4

反応物 2

HCID 313Hydrochloric Acid2 回HCID 106808671-Tert-butoxycarbonylamino-1-cyclopentanecarboxamide

生成物 1

HCID 545931881-Aminocyclopentane-1-carboxamide hydrochloride

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

実験手順

A solution of tert-butyl 1-carbamoylcyclopentylcarbamate (305 mg, 1.33 mmol) in 4N HCl in dioxane (5 mL) and aq. 6N HCl (3 mL) was stirred at room temperature for 3 h. It was then concentrated in vacuo to give 1-aminocyclopentanecarboxamide hydrochloride as a solid (214 mg).

後処理

  1. concentrationIt was then concentrated in vacuo

出典と根拠

ORDレコード
ord-a43fbb7c1ba4499c8a9ed229a92ef8a5
出典データセット
uspto-grants-2014_09
特許番号
US08846928B2

関連ノート

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