Ammonia → Coniferyl Alcohol

HRID 850265

反応式

HRID 850265 の反応式
S(=O)(=O)(O)O.N.[C:7]1([O:17][CH3:18])[C:8](=[CH:10][CH:11]=[C:12]([CH:16]=1)[CH2:13][CH:14]=[CH2:15])[OH:9].C[N+]1C2C(=CC=CC=2)N=C2C=1C=CC=C2.C[O:35]S([O-])(=O)=O>CCCCCCCC.O>[CH2:15]([OH:35])/[CH:14]=[CH:13]/[C:12]1[CH:11]=[CH:10][C:8]([OH:9])=[C:7]([O:17][CH3:18])[CH:16]=1

参加物

7

反応物 4

HCID 222AmmoniaHCID 1118Sulfuric AcidHCID 3314EugenolHCID 9285Phenazine Methosulfate

生成物 1

HCID 1549095Coniferyl Alcohol

試薬・触媒・溶媒 2

HCID 356Octane溶媒HCID 962Water溶媒

実験手順

A dilute sulfuric acid solution or aqueous ammonia was dropwise added to the foregoing reaction solution for enzyme-activity determination from which the buffer is omitted (i.e., a solution comprising 50 μl of a 200 mM solution of eugenol in n-octane, 200 μl of a 50 mM aqueous solution of phenazine methosulfate and 675 μl of deionized water) to adjust the pH thereof from 5 to 7 and the resulting mixture is stirred at a temperature ranging from 25 to 55° C. for 15 to 180 minutes. After the completion of the reaction, the coniferyl alcohol is extracted from the reaction solution with an organic solvent such as ethyl acetate, chloroform, methylene chloride or ethyl ether, followed by purification thereof by a means such as silica gel chromatography, reverse phase liquid chromatography or vacuum distillation, optional discoloration with active carbon and vacuum drying to give colorless coniferyl alcohol powder.

後処理

  1. customAfter the completion of the reaction
  2. extractionthe coniferyl alcohol is extracted from the reaction solution with an organic solvent such as ethyl acetate, chloroform, methylene chloride or ethyl ether
  3. customfollowed by purification
  4. distillationphase liquid chromatography or vacuum distillation, optional discoloration with active carbon and vacuum
  5. customdrying

出典と根拠

ORDレコード
ord-a3ba7078a66245e2acd24ba8e7037606
出典データセット
uspto-grants-2000_01
特許番号
US06017724

関連ノート

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