HCID 563266、化合物 → o-Tyramine
反応式
C([O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH2:15][CH2:16][NH2:17])C1C=CC=CC=1.[H][H]>[C].[Pd].C1COCC1>[OH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH2:15][CH2:16][NH2:17]参加物
5
実験手順
10% Palladium-carbon catalyst (water content 50%, 42 mg) was added to a solution of 2-(2-benzyloxyphenyl)ethylamine (415 mg, 1.826 mmol, 1.0 eq) in THF (10 ml), and the mixture was stirred for 2 hours at room temperature in a stream of hydrogen. The reaction mixture was filtered through Celite, and the filtrate was concentrated under reduced pressure to give 2-(2-hydroxyphenyl)ethylamine (230 mg, 91.8%).
後処理
- filtrationThe reaction mixture was filtered through Celite
- concentrationthe filtrate was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-456c83b17f7b4826b872e24c96a0cd6e
- 出典データセット
- uspto-grants-2000_01
- 特許番号
- US06017919
反応ノート
読み込み中…