Sucrose → (2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol;prop-2-enoate

HRID 850693

反応式

HRID 850693 の反応式
[CH2:1]([OH:23])[C@H:2]1[O:7][C@H:6]([O:8][C@:9]2([CH2:18][OH:19])[O:13][C@H:12]([CH2:14][OH:15])[C@@H:11]([OH:16])[C@@H:10]2[OH:17])[C@H:5]([OH:20])[C@@H:4]([OH:21])[C@@H:3]1[OH:22].COC1C=CC(O)=CC=1.[C:33]([O:37]CC1OC1)(=[O:36])[CH:34]=[CH2:35].[Al]>P([O-])([O-])([O-])=O>[CH2:1]([OH:23])[C@H:2]1[O:7][C@H:6]([O:8][C@:9]2([CH2:18][OH:19])[O:13][C@H:12]([CH2:14][OH:15])[C@@H:11]([OH:16])[C@@H:10]2[OH:17])[C@H:5]([OH:20])[C@@H:4]([OH:21])[C@@H:3]1[OH:22].[C:33]([O-:37])(=[O:36])[CH:34]=[CH2:35]

参加物

6

反応物 4

HCID 5988Sucrose2 回HCID 7836Glycidyl acrylate2 回HCID 90154-MethoxyphenolHCID 5359268Aluminum

生成物 1

HCID 131721615(2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol;prop-2-enoate

試薬・触媒・溶媒 1

HCID 1061Phosphate溶媒

実験手順

Four batches of sucrose acrylate monomers were prepared. For each batch, 10 g of sucrose, 1.9 g of TAB (99%), and a small amount of p-methoxyphenol, which was used as a polymerization inhibitor, were dissolved in 20 ml phosphate buffered aqueous solution (pH 7.2, 0.05 M) in a 200 ml Erlenmeyer flask equipped with magnetic stirrer. The TAB was used as a phase transfer catalyst. Glycidyl acrylate (GA) (Lancaster Synthesis, Inc.; Windham, N.H.) was added to each batch to make sucrose:GA ratios of 1:4, 1:1.5, 1:1:5, and 1:8. The reaction was performed at room temperature with continuous stirring and the flasks were covered with aluminum foil to avoid the light.

後処理

  1. customequipped with magnetic stirrer
  2. customwas performed at room temperature

出典と根拠

ORDレコード
ord-00c5568940204401afab0faf8b41193f
出典データセット
uspto-grants-2000_01
特許番号
US06018033

関連ノート

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