Ethanol → 2-(Butylsulfanyl)cyclopentan-1-one

HRID 851834

反応式

HRID 851834 の反応式
[Na].[CH2:2]([SH:6])[CH2:3][CH2:4][CH3:5].Cl[CH:8]1[CH2:12][CH2:11][CH2:10][CH2:9]1.C([OH:15])C>>[CH2:2]([S:6][CH:9]1[CH2:10][CH2:11][CH2:12][C:8]1=[O:15])[CH2:3][CH2:4][CH3:5]

参加物

5

反応物 4

HCID 702Ethanol2 回HCID 8012ButanethiolHCID 70252ChlorocyclopentaneHCID 5360545Sodium

生成物 1

HCID 229313962-(Butylsulfanyl)cyclopentan-1-one

実験手順

Absolute ethanol (600 ml) was added with metal sodium (13.8 g) and butylmercaptan (64.8 g). A solution of 2-chlorocyclopentane (71.1 g) in absolute ethanol (600 ml) was added to the mixture and then was allowed to stand overnight at a low temperature. The ethanol was removed from the mixture, and the residue was dissolved in ether. The resulting solution was neutralized with aqueous acetic acid solution, the solvent was evaporated, and the resultant was then subjected to distillation, thereby giving 2-buthylthiocyclopentanone (90 g).

後処理

  1. customThe ethanol was removed from the mixture
  2. dissolutionthe residue was dissolved in ether
  3. customthe solvent was evaporated
  4. distillationthe resultant was then subjected to distillation
  5. customgiving 2-buthylthiocyclopentanone (90 g)

出典と根拠

ORDレコード
ord-48e0187831ea4486b732e499f7c4ad21
出典データセット
uspto-grants-2007_08
特許番号
US07252849B2

関連ノート

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