Diisopropylethylamine → (E)-3-(5-bromo-2-methoxy-phenyl)-N-{2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-ethyl}-acrylamide

反応式

[Br:1][C:2]1[CH:3]=[CH:4][C:5]([O:13][CH3:14])=[C:6](/[CH:8]=[CH:9]/[C:10]([OH:12])=O)[CH:7]=1.F[B-](F)(F)F.N1(OC(N(C)C)=[N+](C)C)C2C=CC=CC=2N=N1.C(N(C(C)C)CC)(C)C.[F:46][C:47]1[CH:62]=[CH:61][C:50]([CH2:51][CH:52]2[CH2:57][CH2:56][N:55]([CH2:58][CH2:59][NH2:60])[CH2:54][CH2:53]2)=[CH:49][CH:48]=1>CN(C=O)C>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([O:13][CH3:14])=[C:6](/[CH:8]=[CH:9]/[C:10]([NH:60][CH2:59][CH2:58][N:55]2[CH2:56][CH2:57][CH:52]([CH2:51][C:50]3[CH:49]=[CH:48][C:47]([F:46])=[CH:62][CH:61]=3)[CH2:53][CH2:54]2)=[O:12])[CH:7]=1