3-Methylbenzaldehyde → 4-Iodomethyl-5-methyl-2-m-tolyloxazole

反応式

[I:1][CH2:2][C:3]1[N:4]=[C:5]([C:14]2[CH:19]=[CH:18][C:17](C)=[CH:16][CH:15]=2)[O:6][C:7]=1[C:8]1C=CC=CC=1.[CH3:21]/C(/C(C)=O)=N\O.C1(C)C=CC=C(C=O)C=1>>[I:1][CH2:2][C:3]1[N:4]=[C:5]([C:14]2[CH:15]=[C:16]([CH3:21])[CH:17]=[CH:18][CH:19]=2)[O:6][C:7]=1[CH3:8]

参加物

反応物 3

HCID 121053-Methylbenzaldehyde

HCID 64096332,3-Butanedione monoxime

HCID 574345044-Iodomethyl-5-phenyl-2-p-tolyloxazole

生成物 1

HCID 219803084-Iodomethyl-5-methyl-2-m-tolyloxazole

実験手順

Analogously to the building block synthesis of 4-iodomethyl-5-phenyl-2-p-tolyloxazole, diacetylmonoxime and m-tolualdehyde gave 4-iodomethyl-5-methyl-2-m-tolyloxazole.

出典と根拠

ORDレコード: ord-ee97f07850b04a52a753f40cdc3c2c2e
出典データセット: uspto-grants-2007_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07259177B2

反応ノート

読み込み中…